Resolution: 2.2 Å
EM Method: Helical reconstruction
Fitted PDBs: 8a9l
Q-score: 0.653
Yang Y, Shi Y, Schweighauser M, Zhang X, Kotecha A, Murzin AG, Garringer HJ, Cullinane PW, Saito Y, Foroud T, Warner TT, Hasegawa K, Vidal R, Murayama S, Revesz T, Ghetti B, Hasegawa M, Lashley T, Scheres SHW, Goedert M
Nature (2022) 610 pp. 791-795 [ Pubmed: 36108674 DOI: doi:10.1038/s41586-022-05319-3 ]
- Water (18 Da, Ligand)
- Unknown fragment (627 Da, Protein from Homo sapiens)
- Alpha-synuclein (14 kDa, Protein from human)
- Alpha-synuclein filaments extracted from the human brain with pd, pdd, and dlb (Tissue from Homo sapiens)
- Unknown fragment (783 Da, Protein from Homo sapiens)
The overall structure of human chromatin remodeling PBAF-nucleosome complex
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7vdv
Q-score: 0.315
Yuan JJ, Chen KJ, Zhang WB, Chen ZC
Nature (2022) 605 pp. 166-171 [ DOI: doi:10.1038/s41586-022-04658-5 Pubmed: 35477757 ]
- Histone h4 (11 kDa, Protein from Xenopus laevis)
- Swi/snf complex subunit smarcc2 (133 kDa, Protein from Homo sapiens)
- Swi/snf-related matrix-associated actin-dependent regulator of chromatin subfamily d member 1 (60 kDa, Protein from Homo sapiens)
- Swi/snf-related matrix-associated actin-dependent regulator of chromatin subfamily e member 1 (46 kDa, Protein from Homo sapiens)
- Isoform 2 of bromodomain-containing protein 7 (74 kDa, Protein from Homo sapiens)
- Dna (207-mer) (64 kDa, DNA from synthetic construct)
- Protein polybromo-1 (116 kDa, Protein from Homo sapiens)
- Histone h2b 1.1 (13 kDa, Protein from Xenopus laevis)
- Actin-like protein 6a (47 kDa, Protein from Homo sapiens)
- At-rich interactive domain-containing protein 2,at-rich interactive domain-containing protein 2 (97 kDa, Protein from Homo sapiens)
- Phd finger protein 10 (58 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- Actin, cytoplasmic 1 (41 kDa, Protein from Homo sapiens)
- Histone h3 (15 kDa, Protein from Xenopus laevis)
- Unknown (613 Da, Protein from unidentified)
- Swi/snf-related matrix-associated actin-dependent regulator of chromatin subfamily b member 1 (44 kDa, Protein from Homo sapiens)
- Beryllium trifluoride ion (66 Da, Ligand)
- Unknown (1 kDa, Protein from unidentified)
- Histone h2a (14 kDa, Protein from Xenopus laevis)
- Dna (207-mer) (63 kDa, DNA from synthetic construct)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Isoform 2 of transcription activator brg1 (169 kDa, Protein from Homo sapiens)
- The motor-nucleosome module of human chromatin remodeling pbaf-nucleosome complex (Complex from Homo sapiens)
Smooth muscle myosin shutdown state heads region
Resolution: 6.3 Å
EM Method: Single-particle
Fitted PDBs: 6z47
Q-score: 0.155
Scarff CA, Carrington G, Casas-Mao D, Chalovich JM, Knight PJ, Ranson NA, Peckham M
Nature (2020) 588 pp. 515-520 [ DOI: doi:10.1038/s41586-020-2990-5 Pubmed: 33268888 ]
- Phosphate ion (94 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Smooth muscle myosin in the shutdown state (Complex from Meleagris gallopavo)
- Myosin light chain 9 (19 kDa, Protein from turkey)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Myosin light chain smooth muscle isoform (16 kDa, Protein from turkey)
- Myosin heavy chain 11 (229 kDa, Protein from turkey)
Resolution: 4.3 Å
EM Method: Single-particle
Fitted PDBs: 6xe9
Q-score: 0.266
Yang S, Tiwari P, Lee KH, Sato O, Ikebe M, Padron R, Craig R
Nature (2020) 588 pp. 521-525 [ Pubmed: 33268893 DOI: doi:10.1038/s41586-020-3007-0 ]
- Myosin light chain 9 (19 kDa, Protein from Meleagris gallopavo)
- Smooth muscle myosin ii (530 kDa, Complex from Meleagris gallopavo)
- Myosin light chain smooth muscle isoform (16 kDa, Protein from Meleagris gallopavo)
- Myosin ii heavy chain (smooth muscle) (229 kDa, Protein from Meleagris gallopavo)
Multiple system atrophy Type I alpha-synuclein filament
Resolution: 2.6 Å
EM Method: Helical reconstruction
Fitted PDBs: 6xyo
Q-score: 0.636
Schweighauser M, Shi Y, Tarutani A, Kametani F, Murzin AG, Ghetti B, Matsubara T, Tomita T, Ando T, Hasegawa K, Murayama S, Yoshida M, Hasegawa M, Scheres SHW, Goedert M
Nature (2020) 585 pp. 464-469 [ Pubmed: 32461689 DOI: doi:10.1038/s41586-020-2317-6 ]
Multiple system atrophy Type II-1 alpha-synuclein filament
Resolution: 3.29 Å
EM Method: Helical reconstruction
Fitted PDBs: 6xyp
Q-score: 0.562
Schweighauser M, Shi Y, Tarutani A, Kametani F, Murzin AG, Ghetti B, Matsubara T, Tomita T, Ando T, Hasegawa K, Murayama S, Yoshida M, Hasegawa M, Scheres SHW, Goedert M
Nature (2020) 585 pp. 464-469 [ Pubmed: 32461689 DOI: doi:10.1038/s41586-020-2317-6 ]
Multiple system atrophy Type II-2 alpha-synuclein filament
Resolution: 3.09 Å
EM Method: Helical reconstruction
Fitted PDBs: 6xyq
Q-score: 0.569
Schweighauser M, Shi Y, Tarutani A, Kametani F, Murzin AG, Ghetti B, Matsubara T, Tomita T, Ando T, Hasegawa K, Murayama S, Yoshida M, Hasegawa M, Scheres SHW, Goedert M
Nature (2020) 585 pp. 464-469 [ Pubmed: 32461689 DOI: doi:10.1038/s41586-020-2317-6 ]
Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 5jlh
Q-score: 0.337
von der Ecken J, Heissler SM, Pathan-Chhatbar S, Manstein DJ, Raunser S
Nature (2016) 534 pp. 724-728 [ DOI: doi:10.1038/nature18295 Pubmed: 27324845 ]
- Tropomyosin alpha-3 chain (Protein)
- F-actin (Complex from Dictyostelium discoideum)
- F-actin-myosin-tropomyosin complex (Complex from Homo sapiens)
- Tropomyosin (Complex)
- Actin, cytoplasmic 2 (Protein from Dictyostelium discoideum)
- Myosin (Complex from Homo sapiens)
- Non muscle myosin 2c, alpha-actinin (Protein from Homo sapiens)
A lever-arm rotation drives motility of the minus-end-directed kinesin Ncd.
Endres NF, Yoshioka C, Milligan RA, Vale RD
Nature (2006) 439 pp. 875-878 [ DOI: doi:10.1038/nature04320 Pubmed: 16382238 ]
- Non-claret disjunction nucleotide-free (Sample)
- Ncd (Protein from Bos taurus)
- Tubulin (Protein from Bos taurus)
- Apyrase (Protein from Bos taurus)
A lever-arm rotation drives motility of the minus-end-directed kinesin Ncd.
Endres NF, Yoshioka C, Milligan RA, Vale RD
Nature (2006) 439 pp. 875-878 [ DOI: doi:10.1038/nature04320 Pubmed: 16382238 ]
- Tubulin (Protein from Bos taurus)
- Ncd (Protein from Bos taurus)
- Non-claret disjunction atp, amppnp, state (Sample)